Open AccessPhase-sensitive swept-source optical coherence tomography imaging of the human retina with a vertical cavity surface-emitting laser light source
Author(s) -
WooJhon Choi,
Benjamin Potsaid,
Vijaysekhar Jayaraman,
Bernhard Baumann,
Ireneusz Grulkowski,
Jonathan J. Liu,
Lu Chen,
Alex Cable,
David Huang,
Jay S. Duker,
James G. Fujimoto
Publication year - 2013
Publication title -
optics letters/optics index
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.524
H-Index - 272
eISSN - 1071-2763
pISSN - 0146-9592
DOI - 10.1364/ol.38.000338
Subject(s) - optical coherence tomography , optics , doppler effect , materials science , laser , phase (matter) , coherence (philosophical gambling strategy) , physics , astronomy , quantum mechanics
Despite the challenges in achieving high phase stability, Doppler swept-source/Fourier-domain optical coherence tomography (OCT) has advantages of less fringe washout and faster imaging speeds compared to spectral/Fourier-domain detection. This Letter demonstrates swept-source OCT with a vertical cavity surface-emitting laser light source at 400 kHz sweep rate for phase-sensitive Doppler imaging, measuring pulsatile total retinal blood flow with high sensitivity and phase stability. A robust, simple, and computationally efficient phase stabilization approach for phase-sensitive swept-source imaging is also presented.