Open AccessAssessment of visual function and the neuroretina in subjects diagnosed with congenital anomaly of color vision
Author(s) -
Elena GarcíaMartín,
Juan L Fuentes-Bernal,
Santos Otı́n,
Alida Monreal,
Beatriz Cordón Ciordía,
Elisa Viladés,
Maria I Fuertes-Lazaro
Publication year - 2023
Publication title -
optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 271
ISSN - 1094-4087
DOI - 10.1364/oe.461872
Subject(s) - retina , nerve fiber layer , optical coherence tomography , color vision , retinal , ophthalmology , visual acuity , outer plexiform layer , medicine , external limiting membrane , contrast (vision) , ganglion cell layer , optics , retinal pigment epithelium , physics
This cross-sectional and observational study includes 50 eyes of subjects with color blindness and 50 eyes of control subjects. Visual function (visual acuity, contrast sensitivity, and color vision) and neuroretinal structure were assessed in all subjects using optical coherence tomography (OCT). Significant thinning of the retinal nerve fiber layer, ganglion cell layer, and retina were observed in the color blindness group. Significant thinning was also recorded in layers that involve photoreceptor nuclei (between the outer limiting layer and the Bruch membrane and between the outer plexiform layer and the outer limiting membrane). OCT evaluation based on retinal segmentation is a rapid (5-10 minutes) non-invasive technique and seems to be a good biomarker of color blindness.