Open Access3D reconstruction of weakly scattering objects from 2D intensity-only measurements using the Wolf transform
Author(s) -
Ahmed B. Ayoub,
Joowon Lim,
Elizabeth E. Antoine,
Demetri Psaltis
Publication year - 2021
Publication title -
optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 271
ISSN - 1094-4087
DOI - 10.1364/oe.414543
Subject(s) - optics , refractive index , intensity (physics) , sample (material) , iterative reconstruction , diffraction , scattering , 3d reconstruction , ptychography , materials science , spatial frequency , physics , computer science , artificial intelligence , thermodynamics
A new approach to optical diffraction tomography (ODT) based on intensity measurements is presented. By applying the Wolf transform directly to intensity measurements, we observed unexpected behavior in the 3D reconstruction of the sample. Such a reconstruction does not explicitly represent a quantitative measure of the refractive index of the sample; however, it contains interesting qualitative information. This 3D reconstruction exhibits edge enhancement and contrast enhancement for nanostructures compared with the conventional 3D refractive index reconstruction and thus could be used to localize nanoparticles such as lipids inside a biological sample.