Open AccessElectrochemically directed biofunctionalization of a lossy-mode resonance optical fiber sensor
Author(s) -
Monika Janik,
Paweł Niedziałkowski,
Katarzyna Lechowicz,
Marcin Koba,
Petr Sezemský,
Vítězslav Straňák,
Tadeusz Ossowski,
Mateusz Śmietana
Publication year - 2020
Publication title -
optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 271
ISSN - 1094-4087
DOI - 10.1364/oe.390780
Subject(s) - materials science , indium tin oxide , surface modification , fiber optic sensor , cyclic voltammetry , optical fiber , optoelectronics , optics , fiber , electrode , nanotechnology , electrochemistry , layer (electronics) , composite material , chemistry , physics
In this work, we present a direct electrochemical biofunctionalization of an indium-tin-oxide-coated lossy-mode resonance optical fiber sensor. The functionalization using a biotin derivative was performed by cyclic voltammetry in a 10 mM biotin hydrazide solution. All stages of the experiment were simultaneously verified with optical and electrochemical techniques. Performed measurements indicate the presence of a poly-biotin layer on the sensor's surface. Furthermore, dual-domain detection of 0.01 and 0.1 mg/mL of avidin confirms the sensor's viability for label-free detection.
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