Open AccessParallel multiphoton excited fabrication of tissue engineering scaffolds using a diffractive optical element
Author(s) -
Farid Atry,
Eric C. Rentchler,
Samuel Alkmin,
Bing Dai,
Bin Li,
Kevin W. Eliceiri,
Paul J. Campagnola
Publication year - 2020
Publication title -
optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 271
ISSN - 1094-4087
DOI - 10.1364/oe.381362
Subject(s) - microfabrication , optics , fabrication , lens (geology) , materials science , throughput , microlens , magnification , optoelectronics , computer science , physics , medicine , telecommunications , alternative medicine , pathology , wireless
Multiphoton excited photochemistry is a powerful technique for freeform nano/microfabrication. However, the construction of large and complex structures using single point scanning is slow, where this is a significant limitation for biological investigations. We demonstrate increased throughput via parallel fabrication using a diffractive optical element. To implement an approach with large field of view and near-theoretical resolution, a scan lens was designed that is optimized for using low-magnification high NA objective lenses. We demonstrate that with this approach it is possible to synthesize large scaffolds at speeds several times faster than by single point scanning.