Open AccessMiniature fiber-optic high-intensity focused ultrasound device using a candle soot nanoparticles-polydimethylsiloxane composites-coated photoacoustic lens
Author(s) -
Yao Li,
Zhendong Guo,
Guangyao Li,
SungLiang Chen
Publication year - 2018
Publication title -
optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 271
ISSN - 1094-4087
DOI - 10.1364/oe.26.021700
Subject(s) - materials science , high intensity focused ultrasound , miniaturization , optics , lens (geology) , optical fiber , ultrasound , photoacoustic effect , polydimethylsiloxane , photoacoustic doppler effect , biomedical engineering , optoelectronics , laser , acoustics , nanotechnology , medicine , physics
We present a miniature fiber-optic ultrasound transmitter for generating high-intensity focused ultrasound (HIFU) based on photoacoustic transduction. The HIFU device consists of a fiber and a photoacoustic lens. We develop a simple fabrication procedure for making the photoacoustic lens, which is coated with candle soot nanoparticles-polydimethylsiloxane composites. The fiber is used to deliver pulsed laser for photoacoustic excitation, which facilitates the use of the HIFU device by eliminating the need of free-space optical alignment. The HIFU device (6.5 mm in diameter) produces focused acoustic pressures up to >30 MPa in peak positive with a tight -6-dB focal volume of ~100 μm and ~500 μm in the lateral and axial directions, respectively. Acoustic cavitation induced by the HIFU device is demonstrated. The miniature HIFU device facilitates handheld operation. It holds promise for clinical applications in intraoperative high-precision HIFU therapy. It can even be used for intracavitary therapy with further miniaturization.