Open AccessDifferential Mueller matrix polarimetry technique for non-invasive measurement of glucose concentration on human fingertip
Author(s) -
Quoc Hung Phan,
Yu Lung Lo
Publication year - 2017
Publication title -
optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 271
ISSN - 1094-4087
DOI - 10.1364/oe.25.015179
Subject(s) - mueller calculus , polarimetry , materials science , optics , depolarization , rotation (mathematics) , optical rotation , imaging phantom , matrix (chemical analysis) , scattering , physics , biophysics , mathematics , geometry , biology , composite material
A differential Mueller matrix polarimetry technique is proposed for obtaining non-invasive (NI) measurements of the glucose concentration on the human fingertip. The feasibility of the proposed method is demonstrated by detecting the optical rotation angle and depolarization index of tissue phantom samples containing de-ionized water (DI), glucose solutions with concentrations ranging from 0~500 mg/dL and 2% lipofundin. The results show that the extracted optical rotation angle increases linearly with an increasing glucose concentration, while the depolarization index decreases. The practical applicability of the proposed method is demonstrated by measuring the optical rotation angle and depolarization index properties of the human fingertips of healthy volunteers.