Open AccessOptical digital coherent detection technology enabled flexible and ultra-fast quantitative phase imaging
Author(s) -
Yuanhua Feng,
Xing Lü,
Song Lu,
Xiaojie Guo,
Yawei Wang,
Lingxiao Zhu,
Qi Shu,
Jianping Li,
Kebin Shi,
Zhaohui Li
Publication year - 2016
Publication title -
optics express
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 271
ISSN - 1094-4087
DOI - 10.1364/oe.24.017159
Subject(s) - optics , detector , phase imaging , interferometry , phase (matter) , digital imaging , microscopy , frame rate , image resolution , materials science , computer science , image processing , physics , digital image , computer vision , quantum mechanics , image (mathematics)
Quantitative phase imaging has been an important labeling-free microscopy modality for many biomedical and material science applications. In which, ultra-fast quantitative phase imaging is indispensable for dynamic or transient characteristics analysis. Conventional wide field optical interferometry is a common scheme for quantitative phase imaging, while its data acquisition rate is usually hindered by the frame rate of arrayed detector. By utilizing novel balanced-photo-detector based digital optics coherent detection techniques, we report on a method of constructing ultra-fast quantitative phase microscopy at the line-scan rate of 100 MHz with ~2 μm spatial resolution.