Contrast-enhanced continuous-terahertz-wave imaging based on superparamagnetic iron oxide nanoparticles for biomedical applications | Zendy

Rui Zhang | Zendy; Liangliang Zhang | Zendy; Tong Wu | Zendy; Shasha Zuo | Zendy; Ruixue Wang | Zendy; Cunlin Zhang | Zendy; Jue Zhang | Zendy; Jing Fang | Zendy

Open Access

Contrast-enhanced continuous-terahertz-wave imaging based on superparamagnetic iron oxide nanoparticles for biomedical applications

Author(s) -

Rui Zhang,

Liangliang Zhang,

Tong Wu,

Shasha Zuo,

Ruixue Wang,

Cunlin Zhang,

Jue Zhang,

Jing Fang

Publication year - 2016

Publication title -

optics express

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.394

H-Index - 271

ISSN - 1094-4087

DOI - 10.1364/oe.24.007915

Subject(s) - terahertz radiation , materials science , optics , miniaturization , continuous wave , superparamagnetism , magnetic particle imaging , nanoparticle , contrast (vision) , reflection (computer programming) , magnetic nanoparticles , nuclear magnetic resonance , optoelectronics , magnetic field , nanotechnology , magnetization , laser , physics , computer science , quantum mechanics , programming language

We present a novel contrast-enhanced continuous-terahertz-wave imaging modality based on magnetic induction heating of superparamagnetic iron oxide nanoparticles (SPIOs), which yields a highly sensitive increment in the reflection terahertz (THz) signal in SPIO solution upon exposure to an alternating magnetic field. In the differential and relative refection change focal-plane images before and after alternating magnetic field exposure, a dramatic contrast is demonstrated between water with and without SPIOs. This low-cost, simple, and stable contrast-enhanced continuous-THz-wave imaging system is suitable for miniaturization and real-time imaging application.

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