Open AccessComprehensive analytical model for CW laser induced heat in turbid media
Author(s) -
Hakan Erkol,
Farouk Nouizi,
Alex Luk,
Mehmet Ünlü,
Gültekin Gülşen
Publication year - 2015
Publication title -
optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 271
ISSN - 1094-4087
DOI - 10.1364/oe.23.031069
Subject(s) - heat equation , photon diffusion , optics , laser , continuous wave , diffusion equation , work (physics) , diffusion , materials science , convection–diffusion equation , attenuation coefficient , physics , mechanics , light source , thermodynamics , economy , quantum mechanics , economics , service (business)
In this work, we present a new analytical approach to model continuous wave laser induced temperature in highly homogeneous turbid media. First, the diffusion equation is used to model light transport and a comprehensive solution is derived analytically by obtaining a special Greens' function. Next, the time-dependent bio-heat equation is used to describe the induced heat increase and propagation within the medium. The bio-heat equation is solved analytically utilizing the separation of variables technique. Our theoretical model is successfully validated using numerical simulations and experimental studies with agarose phantoms and ex-vivo chicken breast samples. The encouraging results show that our method can be implemented as a simulation tool to determine important laser parameters that govern the magnitude of temperature rise within homogenous biological tissue or organs.