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Near-field sub-THz transmission-type image system for vessel imaging in-vivo
Author(s) -
TaiLin Tseng,
Shih-Chin Yang,
YuanTa Shih,
YungFong Tsai,
TzungDau Wang,
ChiKuang Sun
Publication year - 2015
Publication title -
optics express
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 271
ISSN - 1094-4087
DOI - 10.1364/oe.23.025058
Subject(s) - optics , terahertz radiation , transmittance , materials science , penetration depth , aperture (computer memory) , wavelength , near and far field , physics , acoustics
A THz near-field transmission imaging system was successfully demonstrated to image the vessels inside the ears of nude mice in vivo. Wave-guided illumination and near-field scanning detection with a sub-wavelength aperture were applied. An operating frequency of 340 GHz was chosen to achieve a higher penetration depth in tissues with a reasonable signal-to-noise ratio. The near-field pattern of the power transmittance through the vessel was also numerically simulated and showed good correspondence to the measured results. The capability of the system for long-term monitoring in vivo was also demonstrated.

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