Open AccessFiber-based source for multiplex-CARS microscopy based on degenerate four-wave mixing
Author(s) -
Thomas Gottschall,
Martin Baumgartl,
Aude Sagnier,
Jan Rothhardt,
César Jáuregui,
Jens Limpert,
Andreas Tünnermann
Publication year - 2012
Publication title -
optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 271
ISSN - 1094-4087
DOI - 10.1364/oe.20.012004
Subject(s) - optics , photonic crystal fiber , four wave mixing , raman scattering , materials science , laser , microscopy , brillouin scattering , wavelength , fiber laser , raman spectroscopy , optoelectronics , physics , nonlinear optics
We present a fiber-based laser source for multiplex coherent anti-Stokes Raman scattering (CARS) microscopy. This source is very compact and potentially alignment-free. The corresponding pump and Stokes pulses for the CARS process are generated by degenerate four-wave mixing (FWM) in photonic-crystal fibers. In addition, an ytterbium-doped fiber laser emitting spectrally narrow 100 ps pulses at 1035 nm wavelength serves as pump for the FWM frequency conversion. The FWM process delivers narrow-band pulses at 648 nm and drives a continuum-like spectrum ranging from 700 to 820 nm. With the presented source vibrational resonances with energies between 1200 cm -1 and 3200 cm -1 can be accessed with a resolution of 10 cm -1 . Additionally, the temporal characteristics of the FWM output have been investigated by a cross-correlation setup, revealing the suitability of the emitted pulses for CARS microscopy. This work marks a significant step towards a simple and powerful all-fiber, maintenance-free multiplex-CARS source for real-world applications outside a laboratory environment.