Open AccessLiving cell imaging by far-field fibered interference scanning optical microscopy
Author(s) -
Jean-Baptiste Decombe,
Wilfrid Schwartz,
Catherine Villard,
Hervé Guillou,
J. Chevrier,
S. Huant,
Jochen Fick
Publication year - 2011
Publication title -
optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 271
ISSN - 1094-4087
DOI - 10.1364/oe.19.002702
Subject(s) - optics , interference microscopy , interferometry , microscopy , microscope , resolution (logic) , optical microscope , interference (communication) , materials science , near field scanning optical microscope , near and far field , depth of field , physics , scanning electron microscope , computer science , computer network , channel (broadcasting) , artificial intelligence
We report on the imaging of biological cells including living neurons by a dedicated fibered interferometric scanning optical microscope. The topography and surface roughness of mouse fibroblasts and hippocampal neurons are clearly revealed. This straightforward far-field technique allows fast, high resolution observation of samples in liquids without lengthy alignment procedures or costly components.