Open Access3D In Vivo optical coherence tomography based on a low-voltage, large-scan-range 2D MEMS mirror
Author(s) -
Jingjing Sun,
Shan Guo,
Lei Wu,
Lin Liu,
Se-woon Choe,
Brian S. Sorg,
Huikai Xie
Publication year - 2010
Publication title -
optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 271
ISSN - 1094-4087
DOI - 10.1364/oe.18.012065
Subject(s) - optical coherence tomography , optics , microelectromechanical systems , materials science , interferometry , transverse plane , preclinical imaging , aperture (computer memory) , physics , optoelectronics , in vivo , structural engineering , acoustics , engineering , microbiology and biotechnology , biology
3D in vivo optical imaging on a mouse has been obtained using a 2D MEMS mirror for lateral scanning in a time-domain optical coherence tomography (OCT) system. The MEMS mirror aperture size is 1 x 1 mm(2), and the device footprint is 2 x 2 mm(2). The MEMS mirror scans +/- 30 degrees optical angles about both x and y-axis at only 5.5V DC voltage. An endoscopic probe with an outer diameter of 5.8 mm has been designed, manufactured and packaged. The probe scans an average transverse area of 2 mm x 2 mm. The imaging speed of the probe is about 2.5 frames per second, limited by the speed of the employed optical delay line.