
RECIST versus volume measurement in medical CT using ellipsoids of known size
Author(s) -
Zachary H. Levine,
Bruce R. Borchardt,
Nolan J. Brandenburg,
Charles W. Clark,
Balasubramanian Muralikrishnan,
Craig M. Shakarji,
Joseph J. Chen,
Eliot L. Siegel
Publication year - 2010
Publication title -
optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 271
ISSN - 1094-4087
DOI - 10.1364/oe.18.008151
Subject(s) - ellipsoid , voxel , materials science , nuclear medicine , coordinate measuring machine , optics , medicine , physics , radiology , astronomy
Two hundred eighty three uniaxial ellipsoids with sizes from 4 mm to 11 mm were measured with a coordinate measuring matching (CMM) and also scanned using a medical computed tomography (CT) machine. Their volumes were determined by counting voxels over a threshold, as well as using equivalent volumes from the length given by the RECIST 1.1 criterion (Response Evaluation Criteria in Solid Tumors). The volumetric measurements yield an order of magnitude reduction in residuals compared to the CMM measurements than the residuals of the RECIST measurements also compared to the CMM measurements.