Open AccessNanodoublers as deep imaging markers for multi-photon microscopy
Author(s) -
Jérôme Extermann,
Luigi Bonacina,
Enrique Cuña,
Christelle Kasparian,
Yannick Mugnier,
Thomas Feurer,
JeanPierre Wolf
Publication year - 2009
Publication title -
optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 271
ISSN - 1094-4087
DOI - 10.1364/oe.17.015342
Subject(s) - optics , microscopy , wavelength , second harmonic generation , laser , materials science , penetration depth , phase imaging , two photon excitation microscopy , biological imaging , phase retrieval , photon , photon counting , multiphoton fluorescence microscope , coherent diffraction imaging , spatial frequency , physics , fourier transform , fluorescence microscope , quantum mechanics , fluorescence
We demonstrate the possibility to excite second-harmonic (SH) active Fe(IO(3))(3) nanocrystals with two distinct laser sources at 800 and 1550 nm, and we show, by a complementary experimental and numerical study, how the wavelength flexibility inherent to non-phase-matched SH nanoparticles can be efficiently exploited to increase imaging penetration depth of markers embedded in biological samples.