Open AccessUltra-high-speed volumetric tomography of human retinal blood flow
Author(s) -
Tilman Schmoll,
Christoph Kolbitsch,
Rainer A. Leitgeb
Publication year - 2009
Publication title -
optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 271
ISSN - 1094-4087
DOI - 10.1364/oe.17.004166
Subject(s) - optical coherence tomography , optics , retinal , doppler effect , tomography , retina , detector , human eye , preclinical imaging , computer science , physics , medicine , ophthalmology , astronomy , microbiology and biotechnology , biology , in vivo
Applying novel detector development based on CMOS technology to Fourier domain optical coherence tomography we achieve depth profile rates up to 200,000 scans/sec. This speed allows for dramatic improvement for imaging small retinal details, such as photo-receptors and capillaries. We demonstrate the impact of this achievable speed to Doppler tomography and discuss advantages as well as short-comings of high speed 3D Doppler imaging of the human retina. Experimental data of 3D static DFDOCT sets from fovea and nerve head region are shown together with first 4D imaging of retinal capillary flow.