Sensitive DNA biosensor based on a long-period grating formed on the side-polished fiber surface | Zendy

Hyun Soo Jang | Zendy; Kwang No Park | Zendy; Jun P. Kim | Zendy; Sang Jun Sim | Zendy; Oh Joon Kwon | Zendy; Young-Geun Han | Zendy; Kyung Shik Lee | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Sensitive DNA biosensor based on a long-period grating formed on the side-polished fiber surface

Author(s) -

Hyun Soo Jang,

Kwang No Park,

Jun P. Kim,

Sang Jun Sim,

Oh Joon Kwon,

Young-Geun Han,

Kyung Shik Lee

Publication year - 2009

Publication title -

optics express

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.394

H-Index - 271

ISSN - 1094-4087

DOI - 10.1364/oe.17.003855

Subject(s) - biosensor , materials science , grating , optics , biomolecule , wavelength , optical fiber , fiber , optoelectronics , nanotechnology , physics , composite material

We demonstrate a sensitive DNA biosensor based on a long period grating (LPG) formed by a photolithograph process on the surface of a side-polished fiber. The biomolecules of the biosensor were immobilized on the silica surface between LPG patterns. The resonance wavelength was red-shifted after the binding of the poly-L-lysine, probe ssDNA and target ssDNA to the sensor surface. The overall wavelength shift after the successful DNA hybridization was 1.82 nm. The proposed LPG-based DNA biosensor is approximately 2.5 times more sensitive than the previously reported fiber grating-based DNA biosensors.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research