
Optical imaging instrument for muscle oxygenation based on spatially resolved spectroscopy
Author(s) -
Khai Jun Kek,
Ryuta Kibe,
Masatsugu Niwayama,
Nobuki Kudo,
Katsuyuki Yamamoto
Publication year - 2008
Publication title -
optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 271
ISSN - 1094-4087
DOI - 10.1364/oe.16.018173
Subject(s) - oxygenation , imaging phantom , vastus medialis , materials science , biomedical engineering , spectroscopy , oxygen saturation , optics , nuclear magnetic resonance , oxygen , chemistry , medicine , physics , electromyography , organic chemistry , quantum mechanics , psychiatry
An imaging instrument based on spatially resolved spectroscopy that enables temporal and spatial analyses of muscle oxygenation was designed. The instrument is portable and can be connected to 32 compact and separate-type optical probes. Its measurement accuracy of O(2) saturation and hemoglobin concentration was evaluated using a tissue-equivalent phantom. Imaging and multi-point measurements of tissue oxygen saturation (S(t)O(2)) in the quadriceps muscle were also performed, and dynamic changes in S(t)O(2) in response to increase in exercise intensity (within the rectus femoris region) and variation in exercise protocol (among the rectus femoris, vastus lateralis and vastus medialis) were clearly shown.