Open AccessEnhancement of laser-induced fluorescence at 473 nm excitation with subwavelength resonant waveguide gratings
Author(s) -
Petri Karvinen,
Tarmo Nuutinen,
Outi Hyvärinen,
Pasi Vahimaa
Publication year - 2008
Publication title -
optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 271
ISSN - 1094-4087
DOI - 10.1364/oe.16.016364
Subject(s) - materials science , optics , fluorescence , grating , laser , dielectric , waveguide , optoelectronics , excitation , diffraction grating , total internal reflection , laser induced fluorescence , physics , electrical engineering , engineering
A dielectric subwavelength resonant waveguide grating was designed and fabricated in order to enhance fluorescence of biomolecules. More than 80 times higher laser-induced fluorescence yield was observed from enhanced green fluorescence protein on the structure when compared to same material on a flat surface.