Open AccessSpecific detection of proteins using photonic crystal waveguides
Author(s) -
Stephen C. Buswell,
Vincent A. Wright,
Jillian M. Buriak,
Vien Van,
Stéphane Evoy
Publication year - 2008
Publication title -
optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 271
ISSN - 1094-4087
DOI - 10.1364/oe.16.015949
Subject(s) - photonic crystal , streptavidin , materials science , refractive index , optics , planar , waveguide , optoelectronics , biotin , chemistry , physics , biochemistry , computer graphics (images) , computer science
Specific detection of proteins is demonstrated using planar photonic crystal waveguides. Using immobilized biotin as probe, streptavidin was captured, causing the waveguide mode cut-off to red-shift. The device was shown to detect a 2.5 nm streptavidin film with a 0.86 nm cut-off red-shift. An improved photonic crystal waveguide sensor design is also described and shown to have a 40% improved bulk refractive index response.