Specific detection of proteins using photonic crystal waveguides | Zendy

Stephen C. Buswell | Zendy; V.A. Wright | Zendy; Jillian M. Buriak | Zendy; Vien Van | Zendy; Stéphane Evoy | Zendy

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Specific detection of proteins using photonic crystal waveguides

Author(s) -

Stephen C. Buswell,

V.A. Wright,

Jillian M. Buriak,

Vien Van,

Stéphane Evoy

Publication year - 2008

Publication title -

optics express

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.394

H-Index - 271

ISSN - 1094-4087

DOI - 10.1364/oe.16.015949

Subject(s) - photonic crystal , streptavidin , materials science , refractive index , optics , planar , waveguide , optoelectronics , biotin , chemistry , physics , biochemistry , computer graphics (images) , computer science

Specific detection of proteins is demonstrated using planar photonic crystal waveguides. Using immobilized biotin as probe, streptavidin was captured, causing the waveguide mode cut-off to red-shift. The device was shown to detect a 2.5 nm streptavidin film with a 0.86 nm cut-off red-shift. An improved photonic crystal waveguide sensor design is also described and shown to have a 40% improved bulk refractive index response.

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