Open AccessIn vivo measurement of erythrocyte velocity and retinal blood flow using adaptive optics scanning laser ophthalmoscopy
Author(s) -
Zhangyi Zhong,
Benno L. Petrig,
Xiaofeng Qi,
Stephen A. Burns
Publication year - 2008
Publication title -
optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 271
ISSN - 1094-4087
DOI - 10.1364/oe.16.012746
Subject(s) - optics , scanning laser ophthalmoscopy , blood flow , adaptive optics , retinal , materials science , laser , biomedical engineering , physics , ophthalmology , medicine
In vivo measurement of retinal blood flow is obtained by measuring the blood velocity of erythrocytes and lumen diameters of the blood vessels using an adaptive optics scanning laser ophthalmoscope. Erythrocyte velocity is measured by tracking erythrocytes moving across a horizontal scanning line. This approach provides high temporal bandwidth measurements, allowing the fluctuation of blood flow during cardiac cycles to be measured. The technique is most applicable to medium-sized blood vessels.