Open AccessAssessment of arterial characteristics in human atherosclerosis by extracting optical properties from polarization-sensitive optical coherence tomography
Author(s) -
Wen Chuan Kuo,
Ming Wei Hsiung,
J. Bruce H. Shyu,
NaiKuan Chou,
P. C. Yang
Publication year - 2008
Publication title -
optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 271
ISSN - 1094-4087
DOI - 10.1364/oe.16.008117
Subject(s) - optical coherence tomography , optics , birefringence , anisotropy , polarization (electrochemistry) , materials science , scattering , scattering coefficient , optical tomography , attenuation coefficient , tomography , physics , chemistry
In this research, we assessed arterial characteristics in human atherosclerosis by determining both scattering and birefringence properties of vessel tissue from polarization-sensitive optical coherence tomography (PS-OCT) images. We demonstrated that optical characteristics including scattering coefficient (mu(s)), effective anisotropy factor (g(eff)), birefringence coefficient (Delta n), and fast-axis angle (beta) of normal and different kinds of atherosclerotic lesions in human vessels can be quantitatively described. Based on our findings, a quantitative PS-OCT image criterion for plaque characterization was constructed.