Open AccessReconstruction of optical absorption coefficient maps of heterogeneous media by photoacoustic tomography coupled with diffusion equation based regularized Newton method
Author(s) -
Zhen Yuan,
Qiang Wang,
Huabei Jiang
Publication year - 2007
Publication title -
optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 271
ISSN - 1094-4087
DOI - 10.1364/oe.15.018076
Subject(s) - attenuation coefficient , optics , photon diffusion , absorption (acoustics) , tomography , diffuse optical imaging , imaging phantom , optical tomography , materials science , tomographic reconstruction , diffusion , photoacoustic effect , diffusion equation , photoacoustic imaging in biomedicine , physics , light source , economy , economics , thermodynamics , service (business)
We describe a novel reconstruction method that allows for quantitative recovery of optical absorption coefficient maps of heterogeneous media using tomographic photoacoustic measurements. Images of optical absorption coefficient are obtained from a diffusion equation based regularized Newton method where the absorbed energy density distribution from conventional photoacoustic tomography serves as the measured field data. We experimentally demonstrate this new method using tissue-mimicking phantom measurements and simulations. The reconstruction results show that the optical absorption coefficient images obtained are quantitative in terms of the shape, size, location and optical property values of the heterogeneities examined.