Open AccessOptical gradient flow focusing
Author(s) -
Yingjie Zhao,
Bryant S. Fujimoto,
Gavin D. M. Jeffries,
Perry G. Schiro,
Daniel T. Chiu
Publication year - 2007
Publication title -
optics express
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 271
ISSN - 1094-4087
DOI - 10.1364/oe.15.006167
Subject(s) - microchannel , optics , pressure gradient , flow (mathematics) , optical force , sorting , focus (optics) , gaussian beam , materials science , radiation pressure , optical tweezers , physics , mechanics , beam (structure) , computer science , programming language
This paper describes a new method for carrying out flow cytometry, which employs optical gradient forces to guide and focus particles in the fluid flow. An elliptically shaped Gaussian beam was focused at the center of a microchannel to exert radiation pressure on suspended nanoparticles that are passing through the channel, such that these particles are guided to the center of the channel for efficient detection and sorting. To verify the efficiency of this optical-gradient-flow-focusing method, we present numerical simulations of the trajectories of the nanoparticles in both electroosmotic flow (EOF) and pressure-driven flow (PDF).