Open AccessDifferential detection of retinal directionality
Author(s) -
Salihah Qaysi,
Denise Valente,
Brian Vohnsen
Publication year - 2018
Publication title -
biomedical optics express
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.9.006318
Subject(s) - optics , fundus (uterus) , retina , prism , retinal , adaptive optics , computer science , physics , light scattering , pupil , scattering , artificial intelligence , computer vision , ophthalmology , medicine
An adaptive optics fundus camera has been developed that uses simultaneous capture of multiple images via adjacent pupil sectors to provide directional sensitivity. In the chosen realization, a shallow refractive pyramid prism is used to subdivide backscattered light from the retina into four solid angles. Parafoveal fundus images have been captured for the eyes of three healthy subjects and directional scattering has been determined using horizontal and vertical differentials. The results for the photoreceptor cones, blood vessels, and the optic disc are discussed. In the case of cones, the observations are compared with numerical simulations based on a simplistic light-scattering model. Ultimately, the method may have diagnostic potential for diseases that perturb the microscopic structure of the retina.