Open AccessNon-contact dynamic diffuse optical tomography imaging system for evaluating lower extremity vasculature
Author(s) -
Jennifer W. Hoi,
H. K. Kim,
Christopher J. Fong,
Lukas Zweck,
Andreas H. Hielscher
Publication year - 2018
Publication title -
biomedical optics express
Language(s) - Danish
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.9.005597
Subject(s) - diffuse optical imaging , optical imaging , biomedical engineering , optics , optical tomography , tomography , computer science , preclinical imaging , tomographic reconstruction , dynamic imaging , materials science , computer vision , image processing , medicine , in vivo , physics , digital image processing , microbiology and biotechnology , biology , image (mathematics)
A novel multi-view non-contact dynamic diffuse optical tomographic imaging system for the clinical evaluation of vasculature in the lower extremities is presented. The system design and implementation are described in detail, including methods for simultaneously obtaining and reconstructing diffusely reflected and transmitted light using a system of mirrors and a single CCD camera. The system and its performance using numeric simulations and optical phantoms. Measurements of a healthy foot in vivo demonstrates the potential of the system in assessing perfusion within the foot.