Non-contact dynamic diffuse optical tomography imaging system for evaluating lower extremity vasculature | Zendy

Jennifer W. Hoi | Zendy; H. K. Kim | Zendy; Christopher J. Fong | Zendy; Lukas Zweck | Zendy; Andreas H. Hielscher | Zendy

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Non-contact dynamic diffuse optical tomography imaging system for evaluating lower extremity vasculature

Author(s) -

Jennifer W. Hoi,

H. K. Kim,

Christopher J. Fong,

Lukas Zweck,

Andreas H. Hielscher

Publication year - 2018

Publication title -

biomedical optics express

Language(s) - Danish

Resource type - Journals

SCImago Journal Rank - 1.362

H-Index - 86

ISSN - 2156-7085

DOI - 10.1364/boe.9.005597

Subject(s) - diffuse optical imaging , optical imaging , biomedical engineering , tomography , computer science , optical tomography , optics , preclinical imaging , tomographic reconstruction , computer vision , in vivo , medicine , physics , microbiology and biotechnology , biology

A novel multi-view non-contact dynamic diffuse optical tomographic imaging system for the clinical evaluation of vasculature in the lower extremities is presented. The system design and implementation are described in detail, including methods for simultaneously obtaining and reconstructing diffusely reflected and transmitted light using a system of mirrors and a single CCD camera. The system and its performance using numeric simulations and optical phantoms. Measurements of a healthy foot in vivo demonstrates the potential of the system in assessing perfusion within the foot.

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