Low-cost compact multispectral spatial frequency domain imaging prototype for tissue characterization | Zendy

Mohsen Erfanzadeh | Zendy; Sreyankar Nandy | Zendy; Patrick D. Kumavor | Zendy; Quing Zhu | Zendy

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Low-cost compact multispectral spatial frequency domain imaging prototype for tissue characterization

Author(s) -

Mohsen Erfanzadeh,

Sreyankar Nandy,

Patrick D. Kumavor,

Quing Zhu

Publication year - 2018

Publication title -

biomedical optics express

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 1.362

H-Index - 86

ISSN - 2156-7085

DOI - 10.1364/boe.9.005503

Subject(s) - multispectral image , optics , materials science , printed circuit board , diffuse optical imaging , characterization (materials science) , preclinical imaging , biological imaging , projection (relational algebra) , computer science , tomography , physics , artificial intelligence , fluorescence , operating system , microbiology and biotechnology , algorithm , in vivo , biology

We present a low-cost, compact, and multispectral spatial frequency domain imaging prototype. Illumination components, including 9 LEDs (660 nm - 950 nm) placed on a custom-designed printed circuit board, linear and rotational motors, a printed sinusoidal pattern, and collimation and projection optics as well as the detection components are incorporated in a compact custom-designed 3D-printed probe. Reconstruction of absorption and reduced scattering coefficients is evaluated via imaging tissue mimicking phantoms and potentials of the probe for biological tissue imaging are evaluated via imaging human ovarian tissue ex vivo .

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