Open AccessLow-cost compact multispectral spatial frequency domain imaging prototype for tissue characterization
Author(s) -
Mohsen Erfanzadeh,
Sreyankar Nandy,
Patrick D. Kumavor,
Quing Zhu
Publication year - 2018
Publication title -
biomedical optics express
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.9.005503
Subject(s) - multispectral image , optics , materials science , printed circuit board , diffuse optical imaging , biological imaging , preclinical imaging , spatial frequency , characterization (materials science) , projection (relational algebra) , biomedical engineering , computer science , physics , tomography , artificial intelligence , fluorescence , in vivo , algorithm , operating system , medicine , microbiology and biotechnology , biology
We present a low-cost, compact, and multispectral spatial frequency domain imaging prototype. Illumination components, including 9 LEDs (660 nm - 950 nm) placed on a custom-designed printed circuit board, linear and rotational motors, a printed sinusoidal pattern, and collimation and projection optics as well as the detection components are incorporated in a compact custom-designed 3D-printed probe. Reconstruction of absorption and reduced scattering coefficients is evaluated via imaging tissue mimicking phantoms and potentials of the probe for biological tissue imaging are evaluated via imaging human ovarian tissue ex vivo .