Open AccessHolmium:yttrium-aluminum-garnet laser induced lithotripsy: in-vitro investigations on fragmentation, dusting, propulsion and fluorescence
Author(s) -
Maximilian Eisel,
Stephan Ströbl,
Thomas Pongratz,
Frank Strittmatter,
Ronald Sroka
Publication year - 2018
Publication title -
biomedical optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.9.005115
Subject(s) - lithotripsy , propulsion , laser , laser lithotripsy , pulse duration , holmium , fragmentation (computing) , yttrium , kidney stones , fluorescence , biomedical engineering , materials science , optics , computer science , medicine , surgery , physics , aerospace engineering , engineering , metallurgy , oxide , operating system
The fragmentation efficiency on Bego artificial stones during lithotripsy and the propulsive effect (via video tracking) was investigated for a variety of laser settings. A variation of the laser settings (pulse energy, pulse duration, repetition rate) altered the total application time required for stone fragmentation, the stone break up time, and the propulsion. The obtained results can be used to develop lithotripsy devices providing an optimal combination of low stone propulsion and high fragmentation efficacy, which can then be evaluated in a clinical setting. Additionally, the fluorescence of human kidney stones was inspected endoscopically in vivo. Fluorescence light can be used to detect stone-free areas or to clearly distinguish calculi from surrounding tissue or operation tools.