Open AccessCiliary muscle thickness profiles derived from optical coherence tomography images
Author(s) -
Sandra Wagner,
Eberhart Zrenner,
Torsten Straßer
Publication year - 2018
Publication title -
biomedical optics express
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.9.005100
Subject(s) - optical coherence tomography , ciliary muscle , emmetropia , optics , accommodation , tomography , materials science , contrast (vision) , pixel , segmentation , optical tomography , sclera , biomedical engineering , computer science , anatomy , physics , artificial intelligence , ophthalmology , medicine , visual acuity , refractive error
The purpose of this study was to provide an in-depth analysis of the ciliary muscle's (CM) morphological changes during accommodation by evaluating CM thickness (CMT) profiles. The CM of 15 near-emmetropic subjects (age 20-39) was imaged via optical coherence tomography (OCT) during far (0 D) and near vision (3 D). A custom-made Java-based program was used for semi-automatic CM segmentation and thickness measurements. CMT profiles were generated to determine regions of the largest shape changes. The results revealed on average a thinning within the first 0.25 mm and a thickening from 0.36 to 1.48 mm posterior to scleral spur when accommodating from 0 to 3 D. In contrast to previous analyses, this method offers pixel-wise reconstruction of CM shapes and quantification of accommodative change across the entire muscle boundary.