Open AccessEnhanced retinal vasculature imaging with a rapidly configurable aperture
Author(s) -
Kaitlyn Sapoznik,
Ting Luo,
Alberto de Castro,
Lucie Sawides,
Raymond L Warner,
Stephen A. Burns
Publication year - 2018
Publication title -
biomedical optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.9.001323
Subject(s) - optics , retinal , adaptive optics , aperture (computer memory) , retina , scanning laser ophthalmoscopy , contrast (vision) , orientation (vector space) , computer science , physics , ophthalmology , medicine , acoustics , geometry , mathematics
In adaptive optics scanning laser ophthalmoscope (AOSLO) systems, capturing multiply scattered light can increase the contrast of the retinal microvasculature structure, cone inner segments, and retinal ganglion cells. Current systems generally use either a split detector or offset aperture approach to collect this light. We tested the ability of a spatial light modulator (SLM) as a rapidly configurable aperture to use more complex shapes to enhance the contrast of retinal structure. Particularly, we varied the orientation of a split detector aperture and explored the use of a more complex shape, the half annulus, to enhance the contrast of the retinal vasculature. We used the new approach to investigate the influence of scattering distance and orientation on vascular imaging.