Open AccessNoninvasive glucose monitoring using mid-infrared absorption spectroscopy based on a few wavenumbers
Author(s) -
Ryosuke Kasahara,
Saiko Kino,
Shunsuke Soyama,
Yuji Matsuura
Publication year - 2017
Publication title -
biomedical optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.9.000289
Subject(s) - wavenumber , absorption (acoustics) , spectroscopy , infrared , near infrared spectroscopy , infrared spectroscopy , materials science , optics , analytical chemistry (journal) , chemistry , chromatography , physics , organic chemistry , quantum mechanics
A method for performing noninvasive blood glucose measurements was developed. The method is based on mid-infrared absorption spectroscopy and uses only a few wavenumbers to measure blood glucose levels in vivo unconditionally. We found that the regression of blood glucose levels using only three wavenumbers, which were selected using a series cross-validation technique, realized accuracies comparable to those of cases in which a greater number of wavenumbers are used. In addition, we demonstrated the performance of this model through correlations among different types of data.