Open AccessConcurrent measurement of skeletal muscle blood flow during exercise with diffuse correlation spectroscopy and Doppler ultrasound
Author(s) -
Chandan-Ganesh Bangalore-Yogananda,
Ryan Rosenberry,
Sagar Soni,
Hanli Liu,
Michael D. Nelson,
Fenghua Tian
Publication year - 2017
Publication title -
biomedical optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.9.000131
Subject(s) - blood flow , ultrasound , medicine , doppler effect , cardiology , skeletal muscle , correlation , biomedical engineering , artifact (error) , doppler ultrasound , hemodynamics , laser doppler velocimetry , nuclear medicine , radiology , psychology , neuroscience , physics , geometry , mathematics , astronomy
Noninvasive, direct measurement of local muscle blood flow in humans remains limited. Diffuse correlation spectroscopy (DCS) is an emerging technique to measure regional blood flow at the microvascular level. In order to better understand the strengths and limitations of this novel technique, we performed a validation study by comparing muscle blood flow changes measured with DCS and Doppler ultrasound during exercise. Nine subjects were measured (all males, 27.4 ± 2.9 years of age) for a rhythmic handgrip exercise at 20% and 50% of individual maximum voluntary contraction (MVC), followed by a post-exercise recovery. The results from DCS and Doppler ultrasound were highly correlated ( R = 0.99 ± 0.02). DCS was more reliable and less susceptible to motion artifact.