Open AccessBlood oxygenation and flow measurements using a single 720-nm tunable V-cavity laser
Author(s) -
Yan Feng,
Haiqin Deng,
Xin Chen,
JianJun He
Publication year - 2017
Publication title -
biomedical optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.8.003516
Subject(s) - laser , materials science , oxygenation , blood flow , wavelength , optics , absorption (acoustics) , optoelectronics , tunable laser , blood oxygenation , grating , tunable diode laser absorption spectroscopy , medicine , physics , anesthesia , composite material , radiology , functional magnetic resonance imaging
We propose and demonstrate a single-laser-based sensing method for measuring both blood oxygenation and microvascular blood flow. Based on the optimal wavelength range found from theoretical analysis on differential absorption based blood oxygenation measurement, we designed and fabricated a 720-nm-band wavelength tunable V-cavity laser. Without any grating or bandgap engineering, the laser has a wavelength tuning range of 14.1 nm. By using the laser emitting at 710.3 nm and 724.4 nm to measure the oxygenation and blood flow, we experimentally demonstrate the proposed method.