Chemical basis for alteration of an intraocular lens using a femtosecond laser | Zendy

Josef F. Bille | Zendy; Johann Engelhardt | Zendy; HansRobert Volpp | Zendy; Abdelmoutalib Laghouissa | Zendy; Marcus Motzkus | Zendy; Zhongxiang Jiang | Zendy; Ruth Sahler | Zendy

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Chemical basis for alteration of an intraocular lens using a femtosecond laser

Author(s) -

Josef F. Bille,

Johann Engelhardt,

HansRobert Volpp,

Abdelmoutalib Laghouissa,

Marcus Motzkus,

Zhongxiang Jiang,

Ruth Sahler

Publication year - 2017

Publication title -

biomedical optics express

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.362

H-Index - 86

ISSN - 2156-7085

DOI - 10.1364/boe.8.001390

Subject(s) - femtosecond , microscopy , raman spectroscopy , refractive index , materials science , laser , optics , raman scattering , microscope , chemistry , optoelectronics , physics

The chemical basis for the alteration of the refractive properties of an intraocular lens with a femtosecond laser was investigated. Three different microscope setups have been used for the study: Laser Induced Fluorescence (LIF) microscopy, Raman microscopy and coherent anti-Stokes Raman Scattering (CARS) microscopy. Photo-induced hydrolysis of polymeric material in aqueous media produces two hydrophilic functional groups: acid group and alcohol group. The spectral signatures identify two of the hydrophilic polar molecules as N-phenyl-4-(phenylazo)-benzenamine (C 18 H 15 N 3 ) and phenazine-1-carboxylic acid (C 13 H 8 N 2 O 2 ). The change in hydrophilicity results in a negative refractive index change in the laser-treated areas.

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