Open AccessThree-dimensional multi-contrast imaging of in vivo human skin by Jones matrix optical coherence tomography
Author(s) -
En Li,
Shuichi Makita,
Young-Joo Hong,
Deepa Kasaragod,
Yoshiaki Yasuno
Publication year - 2017
Publication title -
biomedical optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.8.001290
Subject(s) - optical coherence tomography , optics , birefringence , tomography , diffuse optical imaging , materials science , preclinical imaging , polarization (electrochemistry) , biomedical engineering , in vivo , physics , medicine , chemistry , microbiology and biotechnology , biology
A custom made dermatological Jones matrix optical coherence tomography (JM-OCT) is presented. It uses a passive-polarization-delay component based swept-source JM-OCT configuration, but is specially designed for in vivo human skin measurement. The center wavelength of its probe beam is 1310 nm and the A-line rate is 49.6 kHz. The JM-OCT is capable of simultaneously providing birefringence (local retardation) tomography, degree-of-polarization-uniformity tomography, complex-correlation-based optical coherence angiography, and conventional scattering OCT. To evaluate the performance of this JM-OCT, we measured in vivo human skin at several locations. Using the four kinds of OCT contrasts, the morphological characteristics and optical properties of different skin types were visualized.