Three-dimensional multi-contrast imaging of in vivo human skin by Jones matrix optical coherence tomography | Zendy

En Li | Zendy; Shuichi Makita | Zendy; Young-Joo Hong | Zendy; Deepa Kasaragod | Zendy; Yoshiaki Yasuno | Zendy

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Three-dimensional multi-contrast imaging of in vivo human skin by Jones matrix optical coherence tomography

Author(s) -

En Li,

Shuichi Makita,

Young-Joo Hong,

Deepa Kasaragod,

Yoshiaki Yasuno

Publication year - 2017

Publication title -

biomedical optics express

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.362

H-Index - 86

ISSN - 2156-7085

DOI - 10.1364/boe.8.001290

Subject(s) - optical coherence tomography , optics , birefringence , materials science , tomography , diffuse optical imaging , preclinical imaging , polarization (electrochemistry) , contrast (vision) , biomedical engineering , in vivo , physics , medicine , chemistry , microbiology and biotechnology , biology

A custom made dermatological Jones matrix optical coherence tomography (JM-OCT) is presented. It uses a passive-polarization-delay component based swept-source JM-OCT configuration, but is specially designed for in vivo human skin measurement. The center wavelength of its probe beam is 1310 nm and the A-line rate is 49.6 kHz. The JM-OCT is capable of simultaneously providing birefringence (local retardation) tomography, degree-of-polarization-uniformity tomography, complex-correlation-based optical coherence angiography, and conventional scattering OCT. To evaluate the performance of this JM-OCT, we measured in vivo human skin at several locations. Using the four kinds of OCT contrasts, the morphological characteristics and optical properties of different skin types were visualized.

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