Open AccessLight field otoscope design for 3D in vivo imaging of the middle ear
Author(s) -
Noah Bedard,
Timothy R. Shope,
Alejandro Hoberman,
Mary Ann Haralam,
Nader Shaikh,
Jelena Kovačević,
Nikhil Balram,
Ivana Tošić
Publication year - 2016
Publication title -
biomedical optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.8.000260
Subject(s) - vignetting , optics , optical coherence tomography , curvature , biomedical engineering , medicine , materials science , physics , lens (geology) , mathematics , geometry
We present a light field digital otoscope designed to measure three-dimensional shape of the tympanic membrane. This paper describes the optical and anatomical considerations we used to develop the prototype, along with the simulation and experimental measurements of vignetting, field curvature, and lateral resolution. Using an experimental evaluation procedure, we have determined depth accuracy and depth precision of our system to be 0.05-0.07 mm and 0.21-0.44 mm, respectively. To demonstrate the application of our light field otoscope, we present the first three-dimensional reconstructions of tympanic membranes in normal and otitis media conditions, acquired from children who participated in a feasibility study at the Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center.