Open AccessIntraluminal laser speckle rheology using an omni-directional viewing catheter
Author(s) -
Jing Wang,
Masaki Hosoda,
Diane M. Tshikudi,
Zeinab Hajjarian,
Seemantini K. Nadkarni
Publication year - 2016
Publication title -
biomedical optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.8.000137
Subject(s) - speckle pattern , imaging phantom , catheter , materials science , biomedical engineering , bundle , laser , optics , rotation (mathematics) , rheology , optical fiber , computer science , computer vision , medicine , radiology , physics , composite material
A number of disease conditions in luminal organs are associated with alterations in tissue mechanical properties. Here, we report a new omni-directional viewing Laser Speckle Rheology (LSR) catheter for mapping the mechanical properties of luminal organs without the need for rotational motion. The LSR catheter incorporates multiple illumination fibers, an optical fiber bundle and a multi-faceted mirror to permit omni-directional viewing of the luminal wall. By retracting the catheter using a motor-drive assembly, cylindrical maps of tissue mechanical properties are reconstructed. Evaluation conducted in a test phantom with circumferentially-varying mechanical properties demonstrates the capability of the LSR catheter for the accurate mechanical assessment of luminal organs.