Open AccessMulti-spectral photoacoustic elasticity tomography
Author(s) -
Yubin Liu,
Zhen Yuan
Publication year - 2016
Publication title -
biomedical optics express
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.7.003323
Subject(s) - elasticity (physics) , photoacoustic imaging in biomedicine , photoacoustic tomography , elastic modulus , tomography , materials science , optics , photoacoustic spectroscopy , biomedical engineering , medical imaging , diffuse optical imaging , young's modulus , computer science , physics , composite material , medicine , artificial intelligence
The goal of this work was to develop and validate a spectrally resolved photoacoustic imaging method, namely multi-spectral photoacoustic elasticity tomography (PAET) for quantifying the physiological parameters and elastic modulus of biological tissues. We theoretically and experimentally examined the PAET imaging method using simulations and in vitro experimental tests. Our simulation and in vitro experimental results indicated that the reconstructions were quantitatively accurate in terms of sizes, the physiological and elastic properties of the targets.