Open AccessIdentification of informative bands in the short-wavelength NIR region for non-invasive blood glucose measurement
Author(s) -
Yasuhiro Uwadaira,
Akifumi Ikehata,
Akiko Momose,
Masayo Miura
Publication year - 2016
Publication title -
biomedical optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.7.002729
Subject(s) - wavelength , spectroscopy , optics , materials science , linear regression , intensity (physics) , analytical chemistry (journal) , chemistry , optoelectronics , physics , mathematics , chromatography , statistics , quantum mechanics
The "glucose-linked wavelength" in the short-wavelength near-infrared (NIR) region, in which the light intensity reflected from the hand palm exhibits a good correlation to the blood glucose value, was investigated. We performed 391 2-h carbohydrate tolerance tests (CTTs) using 34 participants and a glucose-linked wavelength was successfully observed in almost every CTT; however, this wavelength varied between CTTs even for the same person. The large resulting data set revealed the distribution of the informative wavelength. The blood glucose values were efficiently estimated by a simple linear regression with clinically acceptable accuracies. The result suggested the potential for constructing a personalized low-invasive blood glucose sensor using short-wavelength NIR spectroscopy.