Frequency domain photoacoustic and fluorescence microscopy
Author(s) -
Gregor Langer,
Bianca Buchegger,
Jaroslaw Jacak,
Thomas A. Klar,
Thomas Berer
Publication year - 2016
Publication title -
biomedical optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.7.002692
Subject(s) - photoacoustic doppler effect , microscopy , optics , fluorescence , materials science , fluorescence microscope , photoacoustic imaging in biomedicine , resolution (logic) , frequency domain , signal (programming language) , time domain , physics , computer science , artificial intelligence , computer vision , programming language
We report on simultaneous frequency domain optical-resolution photoacoustic and fluorescence microscopy with sub-µm lateral resolution. With the help of a blood smear, we show that photoacoustic and fluorescence images provide complementary information. Furthermore, we compare theoretically predicted signal-to-noise ratios of sinusoidal modulation in frequency domain with pulsed excitation in time domain.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom