Open AccessQuantification of the ciliary muscle and crystalline lens interaction during accommodation with synchronous OCT imaging
Author(s) -
Marco Ruggeri,
Carolina De Freitas,
Siobhan Williams,
Víctor Hernández,
Florence Cabot,
Nilüfer Yeşilırmak,
Karam A. Alawa,
Yeon S. Chang,
Sonia H. Yoo,
Giovanni Gregori,
Jean Marie Parel,
Fabrice Manns
Publication year - 2016
Publication title -
biomedical optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.7.001351
Subject(s) - ciliary muscle , accommodation , lens (geology) , anterior eye segment , ciliary body , ciliary processes , presbyopia , optics , anatomy , computer science , physics , ophthalmology , medicine , cornea
Two SD-OCT systems and a dual channel accommodation target were combined and precisely synchronized to simultaneously image the anterior segment and the ciliary muscle during dynamic accommodation. The imaging system simultaneously generates two synchronized OCT image sequences of the anterior segment and ciliary muscle with an imaging speed of 13 frames per second. The system was used to acquire OCT image sequences of a non-presbyopic and a pre-presbyopic subject accommodating in response to step changes in vergence. The image sequences were processed to extract dynamic morphological data from the crystalline lens and the ciliary muscle. The synchronization between the OCT systems allowed the precise correlation of anatomical changes occurring in the crystalline lens and ciliary muscle at identical time points during accommodation. To describe the dynamic interaction between the crystalline lens and ciliary muscle, we introduce accommodation state diagrams that display the relation between anatomical changes occurring in the accommodating crystalline lens and ciliary muscle.