Open AccessFiber-based polarization-sensitive OCT for birefringence imaging of the anterior eye segment
Author(s) -
Masahiro Yamanari,
S. Tsuda,
Taiki Kokubun,
Yukihiro Shiga,
Kazuko Omodaka,
Yû Yokoyama,
Noriko Himori,
Morin Ryu,
Shiho Kunimatsu-Sanuki,
Hidetoshi Takahashi,
Kouichi Maruyama,
Hiroshi Kunikata,
Toru Nakazawa
Publication year - 2015
Publication title -
biomedical optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.6.000369
Subject(s) - optical coherence tomography , optics , anterior eye segment , sclera , birefringence , materials science , medical imaging , polarization (electrochemistry) , physics , computer science , cornea , ophthalmology , medicine , artificial intelligence , chemistry
We demonstrate a prototype system of polarization-sensitive optical coherence tomography (PS-OCT) designed for clinical studies of the anterior eye segment imaging. The system can measure Jones matrices of the sample with depth-multiplexing of two orthogonal incident polarizations and polarization-sensitive detection. An optical clock is generated using a quadrature modulator and a logical circuit to double the clock frequency. Systematic artifacts in measured Jones matrices are theoretically analyzed and numerically compensated using signals at the surface of the sample. Local retardation images of filtering blebs after trabeculectomy show improved visualization of subconjunctival tissue, sclera, and scar tissue of the bleb wall in the anterior eye segment.