Open AccessTwo-dimensional micro-displacement measurement for laser coagulation using optical coherence tomography
Author(s) -
Kazuhiro Kurokawa,
Shuichi Makita,
Young-Joo Hong,
Yoshiaki Yasuno
Publication year - 2014
Publication title -
biomedical optics express
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.6.000170
Subject(s) - optical coherence tomography , laser , optics , materials science , irradiation , biomedical engineering , reproducibility , laser doppler velocimetry , retinal , displacement (psychology) , tomography , coherence (philosophical gambling strategy) , chemistry , physics , ophthalmology , medicine , radiology , psychology , blood flow , chromatography , quantum mechanics , nuclear physics , psychotherapist
To improve the reproducibility of photocoagulation, the ability to quantitatively monitor the thermal change of laser-irradiated retinal tissue is required. Recently, optical coherence tomography has enabled non-invasive and non-contact monitoring of the tissue structural changes during laser irradiation. To further improve the capability of this technique, a method is proposed to measure tissue displacement by simultaneously using Doppler phase shifts and correlation coefficients. The theoretical approach for this method is described, and its performance is experimentally confirmed and evaluated. Finally, lateral and axial displacements in the laser-irradiated retinal tissues of an enucleated porcine eye are observed. The proposed method is found to be useful for further understanding the direct thermal response of laser-irradiated retinal tissue.