Characterization of collagen in non-small cell lung carcinoma with second harmonic polarization microscopy | Zendy

Ahmad Golaraei | Zendy; Richard Cisek | Zendy; Serguei Krouglov | Zendy; Roya Navab | Zendy; Carolyn Niu | Zendy; Shingo Sakashita | Zendy; Kazuhiro Yasufuku | Zendy; MingSound Tsao | Zendy; Brian C. Wilson | Zendy; Virginijus Barzda | Zendy

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Characterization of collagen in non-small cell lung carcinoma with second harmonic polarization microscopy

Author(s) -

Ahmad Golaraei,

Richard Cisek,

Serguei Krouglov,

Roya Navab,

Carolyn Niu,

Shingo Sakashita,

Kazuhiro Yasufuku,

MingSound Tsao,

Brian C. Wilson,

Virginijus Barzda

Publication year - 2014

Publication title -

biomedical optics express

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.362

H-Index - 86

ISSN - 2156-7085

DOI - 10.1364/boe.5.003562

Subject(s) - microscopy , pathology , lung cancer , carcinoma , polarization (electrochemistry) , in vivo , ex vivo , second harmonic generation , materials science , optics , medicine , chemistry , biology , laser , physics , microbiology and biotechnology

Polarization second harmonic microscopy was used for collagen imaging in human non-small cell lung carcinoma and normal lung tissues ex vivo and revealed significant differences in the nonlinear susceptibility component ratio, demonstrating potential use in cancer diagnosis.

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