Open AccessMeasurement of cardiac output by use of noninvasively measured transient hemodilution curves with photoacoustic technology
Author(s) -
Doosun Kang,
Qiaojian Huang,
Youzhi Li
Publication year - 2014
Publication title -
biomedical optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.5.001445
Subject(s) - cardiac output , biomedical engineering , photoacoustic imaging in biomedicine , bolus (digestion) , materials science , imaging phantom , hemodynamics , medicine , anesthesia , nuclear medicine , optics , physics
We present the theoretical basis and experimental verification for cardiac output measurements using noninvasively measured hemodilution curves afforded with an indicator dilution technique and the emerging photoacoustic technology. A photoacoustic system noninvasively tracks a transient hemodilution effect induced by a bolus of isotonic saline as an indicator. As a result, a photoacoustic indicator dilution curve is obtained, which allows to estimate cardiac output from the developed algorithm. The experiments with a porcine blood circulatory phantom system demonstrated the feasibility of this technology towards the development of a noninvasive cardiac output measurement system for patient monitoring.