Measurement of cardiac output by use of noninvasively measured transient hemodilution curves with photoacoustic technology | Zendy

Dongyel Kang | Zendy; Qiaojian Huang | Zendy; Youzhi Li | Zendy

Open Access

Measurement of cardiac output by use of noninvasively measured transient hemodilution curves with photoacoustic technology

Author(s) -

Dongyel Kang,

Qiaojian Huang,

Youzhi Li

Publication year - 2014

Publication title -

biomedical optics express

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.362

H-Index - 86

ISSN - 2156-7085

DOI - 10.1364/boe.5.001445

Subject(s) - cardiac output , biomedical engineering , photoacoustic imaging in biomedicine , bolus (digestion) , materials science , imaging phantom , hemodynamics , medicine , anesthesia , nuclear medicine , optics , physics

We present the theoretical basis and experimental verification for cardiac output measurements using noninvasively measured hemodilution curves afforded with an indicator dilution technique and the emerging photoacoustic technology. A photoacoustic system noninvasively tracks a transient hemodilution effect induced by a bolus of isotonic saline as an indicator. As a result, a photoacoustic indicator dilution curve is obtained, which allows to estimate cardiac output from the developed algorithm. The experiments with a porcine blood circulatory phantom system demonstrated the feasibility of this technology towards the development of a noninvasive cardiac output measurement system for patient monitoring.

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