Open AccessOrientation-independent rapid pulsatile flow measurement using dual-angle Doppler OCT
Author(s) -
Lindsy M. Peterson,
Shi Gu,
Michael W. Jenkins,
Andrew M. Rollins
Publication year - 2014
Publication title -
biomedical optics express
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.5.000499
Subject(s) - pulsatile flow , doppler effect , optics , orientation (vector space) , perpendicular , blood flow , flow (mathematics) , flow velocity , materials science , biomedical engineering , physics , geometry , mathematics , medicine , radiology , astronomy , mechanics , cardiology
Doppler OCT (DOCT) can provide blood flow velocity information which is valuable for investigation of microvascular structure and function. However, DOCT is only sensitive to motion parallel with the imaging beam, so that knowledge of flow direction is needed for absolute velocity determination. Here, absolute volumetric flow is calculated by integrating velocity components perpendicular to the B-scan plane. These components are acquired using two illumination beams with a predetermined angular separation, produced by a delay encoded technique. This technology enables rapid pulsatile flow measurement from single B-scans without the need for 3-D volumetric data or knowledge of blood vessel orientation.