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Multi-color stimulated Raman scattering with a frame-to-frame wavelength-tunable fiber-based light source
Author(s) -
Thomas Würthwein,
Kristin Wallmeier,
Maximilian Brinkmann,
Tim Hellwig,
Niklas M. Lüpken,
Nick S. Lemberger,
Carsten Fallnich
Publication year - 2021
Publication title -
biomedical optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.436299
Subject(s) - optics , raman scattering , ultrashort pulse , materials science , wavelength , raman spectroscopy , laser , optoelectronics , optical fiber , relative intensity noise , physics , semiconductor laser theory
We present multi-color imaging by stimulated Raman scattering (SRS) enabled by an ultrafast fiber-based light source with integrated amplitude modulation and frame-to-frame wavelength tuning. With a relative intensity noise level of -153.7 dBc/Hz at 20.25 MHz the light source is well suited for SRS imaging and outperforms other fiber-based light source concepts for SRS imaging. The light source is tunable in under 5 ms per arbitrary wavelength step between 700 cm -1 and 3200 cm -1 , which allows for addressing Raman resonances from the fingerprint to the CH-stretch region. Moreover, the compact and environmentally stable system is predestined for fast multi-color assessments of medical or rapidly evolving samples with high chemical specificity, paving the way for diagnostics and sensing outside of specialized laser laboratories.

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