Fast diffuse correlation spectroscopy with a low-cost, fiber-less embedded diode laser | Zendy

Arindam Biswas | Zendy; Sadhu Moka | Zendy; Andreas Müller | Zendy; Ashwin B. Parthasarathy | Zendy

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Fast diffuse correlation spectroscopy with a low-cost, fiber-less embedded diode laser

Author(s) -

Arindam Biswas,

Sadhu Moka,

Andreas Müller,

Ashwin B. Parthasarathy

Publication year - 2021

Publication title -

biomedical optics express

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.362

H-Index - 86

ISSN - 2156-7085

DOI - 10.1364/boe.435136

Subject(s) - optics , optical fiber , laser , optical coherence tomography , fiber laser , materials science , spectroscopy , coherence (philosophical gambling strategy) , fiber , diode , noise (video) , biomedical engineering , computer science , optoelectronics , physics , artificial intelligence , medicine , image (mathematics) , quantum mechanics , composite material

Diffuse correlation spectroscopy (DCS), a popular optical technique for fast noninvasive measurement of blood flow, is commonly implemented using expensive fiber-coupled long coherence length laser systems. Here, we report the development of a portable and fiber-less approach that can be used as a low-cost alternative to illuminate tissue in DCS instruments. We validate the accuracy and noise characteristics of the fiber-less DCS laser source, by comparisons against traditional DCS light sources, with experiments on controlled tissue-simulating phantoms and in humans.

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