Open AccessFast diffuse correlation spectroscopy with a low-cost, fiber-less embedded diode laser
Author(s) -
Arindam Biswas,
Sadhu Moka,
Andreas Müller,
Anand Parthasarathy
Publication year - 2021
Publication title -
biomedical optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.435136
Subject(s) - optical fiber , laser , optics , optical coherence tomography , fiber laser , coherence (philosophical gambling strategy) , materials science , spectroscopy , computer science , fiber , diode , noise (video) , biomedical engineering , optoelectronics , physics , artificial intelligence , medicine , image (mathematics) , quantum mechanics , composite material
Diffuse correlation spectroscopy (DCS), a popular optical technique for fast noninvasive measurement of blood flow, is commonly implemented using expensive fiber-coupled long coherence length laser systems. Here, we report the development of a portable and fiber-less approach that can be used as a low-cost alternative to illuminate tissue in DCS instruments. We validate the accuracy and noise characteristics of the fiber-less DCS laser source, by comparisons against traditional DCS light sources, with experiments on controlled tissue-simulating phantoms and in humans.