Open AccessExcitation-scanning hyperspectral video endoscopy: enhancing the light at the end of the tunnel
Author(s) -
Craig M. Browning,
Joshua Deal,
Sam Mayes,
Arslan Arshad,
Thomas C. Rich,
Silas J. Leavesley
Publication year - 2020
Publication title -
biomedical optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.411640
Subject(s) - hyperspectral imaging , endoscopy , spectral imaging , frame rate , computer science , autofluorescence , optics , artificial intelligence , medicine , radiology , physics , fluorescence
Colorectal cancer is the 3 rd leading cancer for incidence and mortality rates. Positive treatment outcomes have been associated with early detection; however, early stage lesions have limited contrast to surrounding mucosa. A potential technology to enhance early stagise detection is hyperspectral imaging (HSI). While HSI technologies have been previously utilized to detect colorectal cancer ex vivo or post-operation, they have been difficult to employ in real-time endoscopy scenarios. Here, we describe an LED-based multifurcated light guide and spectral light source that can provide illumination for spectral imaging at frame rates necessary for video-rate endoscopy. We also present an updated light source optical ray-tracing model that resulted in further optimization and provided a ∼10X light transmission increase compared to the initial prototype. Future work will iterate simulation and benchtop testing of the hyperspectral endoscopic system to achieve the goal of video-rate spectral endoscopy.